When the microbiota is altered, our health system weakens. In the case of children with ASD, it has been shown that the composition of their microbiota is altered. Likewise, there are studies that have suggested that these alterations can contribute to various gastrointestinal and neurological symptoms. Compared to healthy people, the feces of people with ASD have a higher concentration of Clostridia, Bacteroidetes, Desulfovibrio, Sutterella spp, and lower levels of Firmicutes and Verrucomicrobi
60% of our immune system is in the intestine, where there are more than 2,000 different species of bacteria, fungi and yeasts that help us obtain nutrients from the food we eat. Therefore, it was hypothesized that the progression of autism could be caused mainly by the excessive growth of certain bacteria in the intestines of these children, in turn related to the use of antimicrobial agents that suppress other elements of the normal intestinal microbiota.
This project wants to study the results obtained on the microbiota, intestinal permeability, language, behavior and learning, of a probiotic that will be administered to the children of several schools for children with special needs in Madrid, including the Cole de Celia y Pepe. There will be a total of 120 children of which 60 will be with neurological diseases and 60 will be part of the control group. The probiotic, specially manufactured for this project, will be administered for 5 months
Children with neurodevelopmental problems could potentially benefit from the results of this study regardless of the etiology of the same.
This project has provided additional documentation in a PDF file (projdoc.pdf).