Find all causes of Alzheimer's disease and a cure

by Cure Alzheimer's Fund
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Find all causes of Alzheimer's disease and a cure
Find all causes of Alzheimer's disease and a cure
Find all causes of Alzheimer's disease and a cure
Find all causes of Alzheimer's disease and a cure
Find all causes of Alzheimer's disease and a cure

Project Report | Feb 9, 2011
Get your sneakers on, exercise is good!

By Sangram S. Sisodia, PhD | Professor of Neurosciences, University of Chicago

There have been an abundance of preventative measures highlighted in the news about ways to ward off Alzheimer's Disease, everything from curry to crosswords.  And a recent piece in The New York Times suggested many such measures are not valid.  However, while the media can get carried away with some that are far-fetched, there is an accumulating and substantial evidence that suggests physical exercise lowers the risk of developing Alzheimer's.

Cure Alzheimer's Fund-affiliated researcher Sam Sisodia and colleagues have conducted mouse studies that support the anti-Alzheimer's benefits of exercise.

They have found:

  • The positive benefits of exercise on cognition and prevention of age-associated neurodegenerative conditions, including vascular dementia and Alzheimer's disease, are well established.
  • Exercise largely forestalls the onset of amyloid deposits in mice (amyloid deposits are the signature lesions of Alzheimer's).
  • A number of genes are known to be "upregulated" (or turned on) in brains of exercised mice.  This information reveals that the protein products of these genes have a positive influence on decreasing amyloid deposition.
  • Exercise is known to increase the production of neural stem cells and their neuronal differentiation in the hippocampus, a region critical for memory formation.
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Organization Information

Cure Alzheimer's Fund

Location: Wellesley Hills, Ma - USA
Website:
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Project Leader:
Laurel Lyle
Wellesley Hills , MA United States
$94,448 raised of $200,000 goal
 
1,640 donations
$105,552 to go
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