Identify/understand all Alzheimer's-related genes

by Cure Alzheimer's Fund
Vetted

Summary

Cure Alzheimer's Fund is focused on funding research with the highest probability of slowing, stopping or reversing Alzheimer's Disease.
$100,000
total goal
$61,122
remaining
611
donors
1
monthly donor
6
years active

Challenge

The Alzheimer's Genome Project, funded by Cure Alzheimer's Fund, has identified more than 100 candidate genes thought to contribute to or guard against Alzheimer's pathology. Our immediate focus will now be to confirm and prioritize those genes to yield approximately the top two dozen genes that both a) have a high genetic impact (are both prevalent in the general population and play a significant role in AD); and b) influence biological pathways that are most susceptible to drug treatment.

Solution

We will fund research focused on the highest-priority 'hits' as defined by genetic ranking to see what those genes actually do and whether the biological processes in which they are involved might be amenable to modification by drugs.

Long-Term Impact

An estimated 35 million people worldwide have Alzheimer’s, expected to skyrocket to 115 million by 2050. AD is the 6th leading cause of death and is the only one of the major diseases to be increasing in mortality. Research is the key to progress.

Additional Documentation

This project has provided additional documentation in a Microsoft Word file (projdoc.doc).

Resources

http:/​/​www.curealzfund.org
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Organization Information

Cure Alzheimer's Fund

Location: Wellesley Hills, Ma - USA
Website: http:/​/​www.curealz.org
Project Leader:
Laurel Lyle
Wellesley Hills, MA United States
$38,878 raised of $100,000 goal
 
 
782 donations
$61,122 to go
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