Donated tissue used to make "muscle in a dish" for drug research
By June Kinoshita - Chief Strategic Programs Officer
A Fulcrum researcher at work.
Your generous support of our program to deliver muscle tissue from FSH muscular dystrophy patients to researchers has led to the development of an innovative "muscle in a dish" that is now being used for drug discovery. According to a report in Clinical Leader, Massachusetts-based biotech company Fulcrum Therapeutics “is using tissue donated from patients with facioscapulohumeral (FSH) muscular dystrophy...to find a treatment. The tissue is used to create research models that look and respond much like natural human tissues.”
The article goes on to explain, “Since Fulcrum opened for business in 2016, it has built a relationship with the FSH Society, a patient advocacy group championing FSH drug development and clinical trials, as well as funding for research. The group has been critical in helping Fulcrum understand the patient community and develop clinical outcome targets that are meaningful to both patients and families.”
“In addition to helping Fulcrum connect with the patient community, the FSH Society has also worked to draft a tissue protocol for patient donations through the NDRI (National Disease Research Interchange). The FSH Society partnered with the NDRI to create a nationwide registry of individuals with FSH which has been integral in allowing the NDRI collaboration to occur.”
The article explains why primary muscle tissue donated by patients is critical for Fulcrum’s ability to develop a model system for drug testing.
We thank you sincerely for making this breakthrough possible through your support of our tissue donation program.
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