Oral Immunotherapy for Food Allergic Patients

by Friends Association of Shamir (Assaf Harofeh)
Oral Immunotherapy for Food Allergic Patients

Project Report | Sep 12, 2025
Allergenic proteins in diagnosis and innovation

By Michael Goldberg MD, PhD | Project Leader

Dear Friends and supporters,

The summer is coming to a close, and we are finally experiencing some slightly cooler nights. The Jewish New Year is almost upon us, and it is a good time to update you on some things to look ahead to at the Center for Allergy at the Shamir Medical Center.

A New Tool for Better Diagnosis
First thanks to a generous gift, our center recently received a Phadia 250 system, which will allow us to measure IgE levels to a range of specific allergens. Over the past several years, our research has shown that specific IgE testing can be very useful in diagnosing different food allergies, as part of broader diagnostic strategies. This led us to conclude that an analysis system on site at our center would benefit our ongoing work. With the Phadia 250 on site, we will be able to readily do specific IgE tests directly, helping us refine the approaches for when and how they are best used. Ultimately, we hope to reduce the need for oral food challenges—a procedure that, while considered the gold standard” for diagnosing food allergy, is stressful for patients and families, and is not without risk. We are looking forward to embarking very soon on this project.

Collaborating for the Future
Alongside these diagnostic advances, we are also working with colleagues in Israel and abroad to push the science forward. One particularly exciting project focuses on cow’s milk proteins, which are among the most common triggers of food allergy in children. Together with our partners, we are investigating the allergenicity of specific proteins in cow’s milk, with the ambitious goal of creating functional proteins that are truly hypoallergenic.

This project is still in its early stages, but it represents the kind of innovative research that could transform the lives of countless families. Imagine a world where children with cow’s milk allergy could enjoy safe dairy products without fear of a reaction—that’s the vision driving this collaboration. We look forward to sharing more as the project develops.

Neither of these projects would be possible without the help we receve from supporters like you. Your contributions help us build the tools, foster the collaborations, and maintain the momentum needed to tackle food allergy from every angle: better diagnosis, better treatments, and ultimately, better lives for patients and families.

We are deeply grateful for your partnership, and we are excited about what the future holds. With your continued support, we can keep moving toward a safer, healthier world for children with food allergies.

Warm regards and a shana tova umetuka (A good and sweet new year),

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Project Leader:
Michael Goldberg
Beer Yaakov , Israel
$2,948 raised of $48,000 goal
 
139 donations
$45,052 to go
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