Better treatment of Sickle cell disease

Dear donor,

Due to the lack of donations we haven't been able to make a start in the research of yet. We did do a grant application at a large fund in the Netherlands and are awaiting their feedback. The key researcher has been active ovn the subject of Sickle Cell disease. Her latest research publications can be found at:

Minke RAB | Internist-hematologist / Assistant professor | MD PhD | Research profile

Hereby an overview of het 2025 publications:

• Red blood cell properties in hereditary xerocytosis and their response to ex vivo pyruvate kinase activation: a preliminary study.
• Iron Deficiency in HbSC Disease Treated With Repetitive Phlebotomy Is Associated With Fewer Sickle Cell DiseaseRelated Complications
• Metabolomics in sickle cell disease: Current knowledge and gaps – A scoping review
• The use of race and ethnicity in sickle cell disease research
• Red blood cell pyruvate kinase properties in Townes and Berkeley sickle cell disease mouse models – Of mice and men
• Ex vivo activation of pyruvate kinase improves red blood cell metabolism and hydration in hereditary spherocytosis
• Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease
• Oxidantscan: a novel biomarker to assess red blood cell susceptibility to oxidative stress in sickle cell

I you have any questions about this research, or want to know more about how to support it, please contact us.

With kind regards,

Viola Welter

Relationship manager foundations and lotteries

Erasmus MC Foundation ANBI CBF

Postal adress PO 2040, 3000 CA Rotterdam, intern postaladress GK-658, The Netherlands

Office adress room GK-656, Burg. s' Jacobplein 51, 3015 CA Rotterdam, The Netherlands

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E-mail v.welter@erasmusmc.nl | Mobile +31 650 101 897 | Phone +31 10 70 34 802

www.erasmusmc.nl  www.erasmusmcfoundation.nl https://corona.inactievoorerasmusmc.nl/?locale=en

Links:

• Research publications by Minke Rab