It is with great excitement that we announce our 3rd Lynn Sage Scholar, Dr Chonghui Cheng, MD, PhD. Dr. Cheng received her medical degree from Peking University, Beijing, China and her PhD in Biochemistry with Dr. Stewart Shuman at Sloan-Kettering Institute, New York. Dr. Cheng then moved to Boston and did her postdoctoral training with Noble Laureate Phillip Sharp at the Center for Cancer Research, MIT. In August of 2007, Dr. Cheng joined the faculty at the Northwestern University of Hematology/Oncology as an Assistant Professor.
Research in Dr. Cheng's lab focuses on investigating the biological and components and pathways that control tumor metastasis and recurrence, which represent the two major obstacles in the successful treatment of cancer.
For carcinoma cells to break away from neighboring cells and invade to distal organs, they must lose cell-cell contact and become motile and invasive. These changes in cancer cell properties are governed by a process named epithelial-mesenchymal transition (EMT). Currently, the Cheng lab is investigating, at the molecular level, a critical role of several gene products in promoting EMT and breast cancer progression. They hope that their studies on dissecting the mechanisms of EMT and tumor progression may offer new strategies to predict disease prognosis and lead to identification of the therapeutic agents in inhibit EMT, thereby halting tumor progression.
Outside of work, Dr. Cheng enjoys cooking, sightseeing, and spending time with her family.