Our current Scholar, Dr. Virginia Kaklamani has been working to identifying patients at high risk for breast, ovarian and colon cancers based on their genetic background. Dr. Kaklamani has been looking at novel genes and individual risk based on changes in these genes and has been working on several genes and their relation to cancer risk, most notably TGF-beta and adiponectin. One change in TGF-beta has been shown to be associated with increased colon and breast cancer risk in individuals who carry it. Also adiponectin, which is also related to obesity and diabetes, has also been found to change breast and colon cancer risk. The result of this research will help identify correctly high risk patients and offer these individuals better preventative measures (such as oophorectomy) or better screening strategies such as colonoscopies, MRIs of breast and more frequent mammograms.
Dr Kaklamani is also working on identifying risk factors for weight gain in women who are newly diagnosed with breast cancer. It has been shown that women with breast cancer gain weight and this weight gain increases the chance of recurrence of their cancer. Dr Kaklamani has initiated a study to evaluate breast cancer related weight gain, looking at genes that may be responsible for the weight gain as well as treatment related effects.
“The Lynn Sage Foundation has given me the support to examine the role of obesity and obesity related genes in breast cancer. This will help our breast cancer patients live longer and better lives.”
-Virginia Kaklamani, MD, DSc, Assistant Professor, Division of Hematology/Oncology
As October, quickly approaches, we’re gearing up for our third annual Chicago’s In Good Taste Campaign. This campaign unites local businesses, predominantly restaurants, during Breast Cancer Awareness Month. The ultimate goal for the participating restaurants, dining services, spas and other organizations is to raise money for breast cancer research. When guests dine at the participating establishments or utilize participating services, patrons have the option to donate $1 or more to the Lynn Sage Foundation on the receipt of their purchase. Table cards, check presenters and posters explaining Chicago’s In Good Taste are provided to all partners. All donations generated benefit the Lynn Sage Scholars Program at Northwestern University. Last year we has over 100 participating restaurants and raised over $30,000.
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