PATH

PATH is the leader in global health innovation. An international nonprofit organization, we save lives and improve health, especially among women and children. We accelerate innovation across five platforms-vaccines, drugs, diagnostics, devices, and system and service innovations-that harness our entrepreneurial insight, scientific and public health expertise, and passion for health equity. By mobilizing partners around the world, we take innovation to scale, working alongside countries primarily in Africa and Asia to tackle their greatest health needs. Together, we deliver measurable results that disrupt the cycle of poor health.
Nov 20, 2013

Vaccine cuts incidence of meningitis by 94 percent in Chad

September opened with exhilarating news: A study published in the medical journal The Lancet found the MenAfriVac® vaccine lowered the rate of new cases of meningitis by 94 percent following a 2011 immunization campaign in Chad, West Africa. The study drew global attention to the Meningitis Vaccine Project, a collaboration led by PATH and the World Health Organization (WHO) that developed the MenAfriVac® vaccine.

To evaluate the effectiveness of the mass immunization campaigns, researchers compared the number of new cases of meningitis of any kind in regions with and without vaccination during the 2012 season. They found that the rate was 43.6 per 100,000 people in regions where vaccination did not take place, compared to only 2.5 per 100,000 among those who were vaccinated—a stunning difference. None of the observed cases were caused by group A meningitis. In addition, they found no cases of meningitis among people who lived in vaccination areas but were too young or old to participate. This suggests that the vaccine provides “herd immunity,” helping to protect unvaccinated people by reducing the presence of the disease in their communities.

Additional vaccine rollouts in sub-Saharan Africa are continuing this momentum. In September, a campaign in Sudan reached more than 6.3 million people. And recent introductions in Ethiopia and Nigeria, together with a late-November campaign in The Gambia, will bring MenAfriVac® to millions more. By the end of this year, the total number of young Africans vaccinated since 2010 is expected to reach an astounding 150 million.

Your support is contributing to these and other efforts, bringing tangible hope to families throughout sub-Saharan Africa. Thank you!

The Meningitis Vaccine Project (MVP) is a partnership between PATH and the World Health Organization. Started in 2001 with funding from the Bill & Melinda Gates Foundation, the mission of the MVP is to eliminate meningitis as a public health problem in sub-Saharan Africa through the development, testing, introduction, and widespread use of conjugate meningococcal vaccines. MenAfriVac® is a registered trademark of Serum Institute of India Ltd.

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Aug 21, 2013

Meningitis cases reach a 10-year low

A summer report by the World Health Organization (WHO) brings encouraging news for the fight against epidemic meningitis in sub-Saharan Africa. The number of cases reported during the 2013 epidemic season was the lowest it’s been in a decade. The decrease in cases is thought to be due to the introduction of MenAfriVac®—a vaccine developed by PATH and WHO through the Meningitis Vaccine Project.

Plans are under way for the continued rollout of MenAfriVac® across Africa’s meningitis belt. To date, 10 out of 26 countries have launched mass vaccination campaigns, and by the end of this year, another 2 will join them. The Gambia will vaccinate its whole population of 1- to 29-year-olds (about 1.2 million people), while Ethiopia will take a staggered approach, vaccinating 20 million people this fall in the first of three phases. Nigeria and Sudan will continue their phased introduction of MenAfriVac®.

By the close of 2013, more than 150 million young Africans will have received the lifesaving vaccine since it was first introduced in 2010. This progress wouldn’t be possible without generous contributions from donors. Thank you so much for your support!

MenAfriVac is a registered trademark of Serum Institute of India Ltd.

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May 24, 2013

Everyday hope: Safely expanding MenAfriVac

MenAfriVac brings hope to millions of Africans.
MenAfriVac brings hope to millions of Africans.

Outbreaks of deadly and debilitating meningococcal A meningitis once stopped many African communities in their tracks. Now, however, more than 103 million people carry a new hope—protection gained from the MenAfriVac® vaccine. Immunity with just one dose is expected to be long lasting, and as of this update, there has not been a single reported case in a person who has been vaccinated.

With help from you and other partners, the Meningitis Vaccine Project (MVP)—a collaboration between PATH and the World Health Organization—is reaching more people each year. Mass immunization campaigns will introduce MenAfriVac® in Ethiopia and The Gambia in 2013. These efforts—combined with the ongoing rollout of the vaccine in Nigeria and Sudan—could protect 50 million more people in the current age group (1 to 29 years) by the end of the year.

At the same time, we’re thinking even bigger (and smaller): What if infants received this lifesaving protection as part of routine immunizations? Primary results from infant clinical trials are very promising, and we hope to introduce the MenAfriVac® vaccine in routine immunization programs in a couple of years’ time.

Your support is helping MVP bring lifesaving MenAfriVac® to more communities and building a foundation to sustain this crucial protection for years to come. Thank you!

MenAfriVac®, a registered trademark of Serum Institute of India Ltd., was developed by PATH and the World Health Organization, working with two dozen global collaborators.

Photo: PATH/Gabe Bienczycki.

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